IL-10: A Multifunctional Cytokine in Viral Infections

IL-10: A Multifunctional Cytokine in Viral Infections

Blog Article

The anti-inflammatory click here master regulator IL-10 is critical to protect the host from tissue damage during acute phases of immune responses.This regulatory mechanism, central to T cell homeostasis, can be hijacked by viruses to evade immunity.IL-10 can be produced by virtually all immune cells, and it can also modulate the function of these cells.Understanding the effects of this multifunctional cytokine is therefore a complex task.In the present review we discuss verona wig the factors driving IL-10 production and the cellular sources of the cytokine during antiviral immune responses.

We particularly focus on the IL-10 regulatory mechanisms that impact antiviral immune responses and how viruses can use this central regulatory pathway to evade immunity and establish chronic/latent infections.